What Will 100mg Of Sildenafil Do?

Are you curious about the effects of taking 100mg of Sildenafil? This article will give you a brief insight into what to expect when you consume this medication. Sildenafil is a commonly prescribed drug used to treat erectile dysfunction, and by taking a closer look at the effects of a 100mg dosage, you’ll be informed and prepared. Let’s explore the fascinating world of Viagra’s famous active ingredient and discover what it can do for you!

What is Sildenafil?

Sildenafil is a medication commonly used to treat erectile dysfunction and pulmonary arterial hypertension. It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. Sildenafil works by relaxing the muscles in the walls of blood vessels and increasing blood flow to specific areas of the body.


Sildenafil is a prescription medication that helps men with erectile dysfunction achieve and maintain an erection. It is also used to treat pulmonary arterial hypertension by reducing blood pressure in the arteries of the lungs.

Mechanism of Action

Sildenafil works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for breaking down cyclic guanosine monophosphate (cGMP). By inhibiting PDE5, sildenafil allows cGMP to accumulate and promote the relaxation of smooth muscles in the blood vessels. This relaxation increases blood flow to the penis, leading to improved erections in men with erectile dysfunction. In the case of pulmonary arterial hypertension, sildenafil reduces the constriction of blood vessels in the lungs, leading to decreased pulmonary blood pressure.

100mg Sildenafil Dosage

Typical Dosage

The typical starting dose of sildenafil for erectile dysfunction is 50mg, taken approximately one hour before sexual activity. However, your doctor may prescribe a higher or lower dose depending on your individual needs. The maximum recommended dose is 100mg per day.


It is important to follow your doctor’s instructions regarding dosage and timing. Sildenafil should not be taken more than once a day. It is recommended to take sildenafil on an empty stomach or after a light meal, as a heavy or high-fat meal may delay its effectiveness.

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Dosage Adjustments

Your doctor may adjust your dosage of sildenafil based on your response to the medication and any side effects you may experience. If you do not achieve the desired effect with the initial dose, your doctor may increase the dosage. Conversely, if you experience bothersome side effects, your doctor may lower the dosage. It is crucial to communicate with your healthcare provider about any concerns or changes in your health status.

Erectile Dysfunction Treatment

Improvement in Erections

Sildenafil has been proven to significantly improve erectile function in men with erectile dysfunction. It helps increase blood flow to the penis, resulting in firmer and longer-lasting erections. With the appropriate sexual stimulation, sildenafil can enable men to achieve satisfactory sexual experiences.

Response Time

Sildenafil starts working within 30 to 60 minutes after ingestion. However, the response time may vary from person to person, depending on factors such as body weight, metabolism, and underlying health conditions. It is important to plan your sexual activity accordingly, considering the timeframe for sildenafil to take effect.

Duration of Effect

The effects of sildenafil can last up to four to six hours, providing a window of opportunity to engage in sexual activity. It is important to note that individual response may vary, and the duration of effect can be influenced by factors such as age, overall health, and the presence of certain medications or medical conditions.


Many men who use sildenafil for the treatment of erectile dysfunction report high levels of satisfaction. The ability to achieve and maintain an erection can have a positive impact on overall sexual confidence and satisfaction in intimate relationships. However, it is important to remember that individual experiences may vary, and it is crucial to communicate openly with your partner and healthcare provider about any concerns or difficulties you may have.

Pulmonary Arterial Hypertension Treatment

Reducing Pulmonary Blood Pressure

Sildenafil is an effective treatment for pulmonary arterial hypertension by reducing blood pressure in the arteries of the lungs. By inhibiting the enzyme PDE5, sildenafil relaxes the walls of blood vessels in the lungs, allowing blood to flow more freely and reducing the strain on the heart.

Improved Exercise Capacity

Sildenafil has been shown to improve exercise capacity in individuals with pulmonary arterial hypertension. By reducing pulmonary blood pressure and improving blood flow, sildenafil allows patients to engage in physical activities with less effort and discomfort.

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Delay Disease Progression

In addition to its symptom-relieving effects, sildenafil may also help delay the progression of pulmonary arterial hypertension. By improving blood flow and reducing the strain on the heart, sildenafil may slow down the deterioration of heart function and potentially improve long-term outcomes for patients with this condition.

Potential Side Effects

Common Side Effects

Like any medication, sildenafil can cause certain side effects. The most common ones include headaches, facial flushing, indigestion, nasal congestion, and dizziness. These side effects are usually mild and temporary, resolving on their own without medical intervention.

Rare Side Effects

Although rare, more severe side effects of sildenafil may include priapism (a painful and prolonged erection lasting more than four hours), sudden vision loss, or sudden hearing loss. If any of these rare side effects occur, it is essential to seek immediate medical attention.

Serious Side Effects

In some cases, sildenafil can interact with other medications or underlying health conditions, leading to more serious side effects. These may include a drop in blood pressure, allergic reactions, or cardiovascular events such as a heart attack or stroke. It is crucial to disclose your medical history and any medications you are taking to your doctor before starting sildenafil therapy.


Certain precautions should be taken when using sildenafil. It is important to avoid grapefruit or grapefruit juice while taking sildenafil, as they can increase the levels of the medication in your body and potentially lead to an overdose. Additionally, if you have a history of cardiovascular disease, liver or kidney impairment, or certain eye conditions, extra caution should be exercised when using sildenafil. Always consult with your healthcare provider to determine if sildenafil is safe and appropriate for you.

Interactions and Contraindications

Drug Interactions

Sildenafil can interact with several medications, including nitrates (used to treat chest pain), alpha-blockers (used to treat high blood pressure), certain antifungal and antibiotic drugs, and HIV protease inhibitors. These interactions can increase the risk of side effects or potentially dangerous drops in blood pressure. It is vital to inform your doctor about all the medications you are taking to ensure their compatibility with sildenafil.

Alcohol and Sildenafil

Drinking alcohol in moderation is generally considered safe while taking sildenafil. However, excessive alcohol consumption can impair sexual function and increase the risk of side effects such as dizziness or low blood pressure. It is recommended to consume alcohol in moderation or avoid it altogether when taking sildenafil.

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Sildenafil is contraindicated in certain situations, including if you are currently taking nitrates or nitric oxide donors, have a known allergy to sildenafil or any of its components, or have experienced a recent heart attack or stroke. It is essential to discuss your medical history with your doctor to determine if sildenafil is safe for you.

Effectiveness in Women

Limited Efficacy in Women

Sildenafil has primarily been studied and approved for use in men with erectile dysfunction. Its effectiveness in treating sexual dysfunction in women is limited and not widely supported by clinical evidence. Other treatment options may be more suitable for women experiencing sexual difficulties.

Use in Specific Conditions

However, there are certain conditions, such as female sexual arousal disorder, where sildenafil may be prescribed off-label for women. These cases should be individually assessed and monitored by a healthcare professional. It is important to have an open and honest discussion with your doctor regarding potential treatment options for any sexual health concerns.

Effectiveness in Older Adults

Similar Effectiveness

Sildenafil is equally effective in older adults as it is in younger individuals. Age alone does not significantly impact the efficacy of sildenafil in treating erectile dysfunction or pulmonary arterial hypertension. However, older adults often have a higher prevalence of underlying health conditions and are more likely to take medications that can interact with sildenafil. Therefore, careful monitoring and dosage adjustments may be necessary.

Consideration for Dosage Adjustments

Older adults may require dosage adjustments due to age-related changes in metabolism and potential interactions with other medications. It is crucial to work closely with your doctor to determine the appropriate dosage and monitor for any side effects or interactions to ensure safe and effective treatment.

Other Uses of Sildenafil

Raynaud’s Phenomenon

Sildenafil may be used off-label to treat Raynaud’s phenomenon, a condition characterized by the constriction of blood vessels in response to cold or stress. By relaxing blood vessels and improving blood flow, sildenafil can help relieve symptoms and reduce the frequency and severity of Raynaud’s attacks.

Altitude Sickness

Sildenafil has also been explored as a potential treatment for altitude sickness, a condition that occurs at high altitudes due to decreased oxygen levels and increased blood vessel constriction. However, its use for this purpose is still being studied, and further research is needed to determine its effectiveness and optimal dosage.


Sildenafil is a medication that has proven to be effective in treating erectile dysfunction and pulmonary arterial hypertension. It works by increasing blood flow to specific areas of the body, resulting in improved erections in men and reduced pulmonary blood pressure in patients with hypertension. While sildenafil has shown positive results in many cases, individual responses may vary, and it is important to consult with a healthcare professional before starting or adjusting the dosage of sildenafil. They will guide you through the appropriate dosage, potential side effects, and any necessary precautions to ensure the safe and effective use of this medication.